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The Japanese word

一生懸命

is pronounced
isshoukenmei | いっしょうけんめい
means
as well as one can, as hard as one can {exp}
Examples:
由美は英語を一生懸命勉強する。
yumi wa eigo o isshōkenmei benkyō suru.
Yumi studies English hard.
落第しないように一生懸命勉強しなさい。
rakudai shi nai yō ni isshōkenmei benkyō shi nasai.
Study hard so you don't fail. | You must study hard lest you fail.
落第しないように一生懸命に勉強しなさい。
rakudai shi nai yō ni isshōkenmei ni benkyō shi nasai.
Study hard so you don't fail.
僕は今日は一生懸命働く様な気分じゃない。
boku wa kyō wa isshōkenmei hataraku yō na kibun ja nai.
I am not in the humor for working hard today.
母は私たちを育てるために一生懸命働いた。
haha wa watashi tachi o sodateru tame ni isshōkenmei hatarai ta.
My mother worked hard in order to rear us. | My mother worked hard in order to raise us.
僕は今後もっと一生懸命勉強する決意をした。
boku wa kongo motto isshōkenmei benkyō suru ketsui o shi ta.
I've made up my mind to study harder from now on.
一生懸命指でまぶたを広げて目薬を差しました。
isshōkenmei yubi de mabuta o hiroge te megusuri o sashi mashi ta.
With great effort I held his eyelids open with my fingers and dropped in the eye medicine.
彼女は生計をたてるため、一生懸命働いている。
kanojo wa seikei o tateru tame, isshōkenmei hatarai te iru.
She works hard to earn her living.
母さんがあまり一生懸命に勉強するなと言うのです。
kāsan ga amari isshōkenmei ni benkyō suru na to iu no desu.
Mother tells me not to study so hard. | My mother tells me not to study so hard.
来年はもっと一生懸命に勉強しなければいけませんよ。
rainen wa motto isshōkenmei ni benkyō shi nakere ba ike masen yo.
You will have to study harder next year.
入学試験に落ちないように、彼女は一生懸命に勉強した。
nyūgaku shiken ni ochi nai yō ni, kanojo wa isshōkenmei ni benkyō shi ta.
She studied hard in order not to fail the entrance exam.
疲れているならそんなに一生懸命勉強しなくてもよいです。
tsukare te iru nara sonnani isshōkenmei benkyō shi naku te mo yoi desu.
You don't have to work so hard if you're tired.
毎日一生懸命に英語を勉強したが、あまり身につかなかった。
mainichi isshōkenmei ni eigo o benkyō shi ta ga, amari mi ni tsuka nakatta.
I studied English very hard every day, but I didn't learn a lot.
とってもいい会社ですよ。社長は凄腕だし、社員はみんな一生懸命だよ。
tottemo ī kaisha desu yo. shachō wa sugōde da shi, shain wa minna isshōkenmei da yo.
It's a very good company! The president is a real go-getter and the workers all put in their best.
良い大学に入るためには、あなたは一生懸命勉強するだけでよいのです。
yoi daigaku ni hairu tame ni wa, anata wa isshōkenmei benkyō suru dake de yoi no desu.
All you have to do is study hard to get into a good college.
一生懸命磨きました。困ったのは、意外と低級宝石のストックがないことです。
isshōkenmei migaki mashi ta. komatta no wa, igaito teikyū hōseki no sutokku ga nai koto desu.
I polished for all I was worth. The trouble is that my stock of low-grade gems was surprisingly low.
野球選手になりたいというあなたの夢は、一生懸命に努力すれば実現するでしょう。
yakyū senju ni nari tai toyū anata no yume wa, isshōkenmei ni doryoku sure ba jitsugen suru desho u.
Your dream of becoming a baseball player will come true if you try hard.
必死で考えた企画は却下、一生懸命作った本は売れない。山下さんは八方塞がりの状態に陥っている。
hisshi de kangae ta kikaku wa kyakka, isshōkenmei tsukutta hon wa ure nai. yamashita san wa happōfusagari no jōtai ni ochītte iru.
Yamashita is stuck with no way out. His well-thought-out project was rejected and the books he worked really hard on aren't selling.
一生懸命作られたゲームには、一生懸命に取り組むのが礼儀なんだよ?ポーズボタンなんて押したらゲームに失礼だもん。
isshōkenmei tsukura re ta gēmu ni wa, isshōkenmei ni torikumu no ga reigi nan da yo? pōzu botan nante oshi tara gēmu ni shitsurei da mon.
It's only manners to tackle all out a game that they have gone all out in creating. Pressing the pause button is just rude!
Examples sourced from tatoeba.org